Analysis of DSA Epitopes and FXM

This project requires serum, DNA & cells of donor/recipient pairs where DSA present, testing to be performed using standardized SOPs, custom and commercial reagents. Testing includes IgG SAB I, IgG SAB II, Bio-C1q SAB I, Bio-C1q SAB II and DSA-FXM, DNA or complete HLA typing information by NGS HLA from donor/recipient pairs. Analysis: DSA FXM, other FXM methods when available, pre and post-Transplant antibody results and transplant outcomes. Donor pairs may be from Kidney or Heart Transplant pairs but must be single organ primary Transplants.

Project Leader: Dolly Tyan (dtyan@stanford.edu)

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